Sulfazin 500mg Tablet 10pcs

✔️ Uses of Sulfazin 500

• Rheumatoid arthritis
• Ulcerative colitis
• Crohn’s disease
• Ankylosing spondylitis

✔️ Benefits of Sulfazin 500

• Sulfazin 500 functions by reducing inflammation in the colon. It works by inhibiting the production of prostaglandins, chemicals responsible for controlling inflammation.
• This action helps alleviate inflammation in various areas, including the joints, skin, and intestines.
• As a result, it is effective in treating a broad range of conditions such as ulcerative colitis, Crohn's disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and juvenile idiopathic arthritis.
• It is important to note that Sulfazin 500 is not a pain reliever but an anti-inflammatory medication designed to target the underlying inflammation in these conditions.

✔️ Ulcerative Colitis:

A chronic inflammatory condition affects the bowels, causing irritation, inflammation, and ulcers in the lining of the large intestine (colon).

✔️ Crohn’s Disease:

A type of inflammatory bowel disease (IBD) marked by persistent inflammation of the digestive tract, which can affect any part of the gastrointestinal system.

✔️ Psoriasis:

A chronic skin condition where skin cells multiply at an accelerated rate, resulting in raised, red patches covered with silvery-white scales.

✔️ Rheumatoid Arthritis and Ankylosing Spondylitis:

Common rheumatic diseases that cause inflammation of the joints and spine. They lead to chronic pain, stiffness, and inflammation, which can progressively result in disability if untreated.

✔️ Dosage Guidelines for Sulfasalazine:

Adult Dose

Oral (Inflammatory Bowel Disease):

• Initial Dose: 1-2 g, four times daily until remission.
• Maintenance Dose: 2 g/day in divided doses.

Oral (Rheumatoid Arthritis):

• Initial Dose: 500 mg daily during the first week.
• Increase the dose by 500 mg weekly.
• Maximum Dose: 3 g/day in 2-4 divided doses.

Rectal (Inflammatory Bowel Disease):

• Dose: 0.5-1 g in the morning and at night, either alone or alongside oral treatment.

Hepatic Impairment:

• Avoid use.

Child Dose

Oral (Inflammatory Bowel Disease):

• Children >2 years: 40-60 mg/kg/day in divided doses.
• Maintenance Dose: 20-30 mg/kg/day in divided doses.

Oral (Rheumatoid Arthritis):

• For polyarticular juvenile rheumatoid arthritis (children >6 years):
  • Dose: 30-50 mg/kg/day in two divided doses.
  • Start with 1/4 to 2/3 of the expected maintenance dose and increase weekly to reach the maintenance dose in one month.
  • Maximum Dose: 2 g/day.

Rectal (Inflammatory Bowel Disease):

• Ages 5-8 years: 500 mg twice daily.
• Ages 8-12 years: 500 mg in the morning and 1 g at night.
• Ages 12-18 years: 1 g twice daily.

✔️ Instructions for Use: Sulfazin 500

• Take Sulfazin 500 exactly as advised by your physician.
• Swallow the tablet whole with water. Do not crush or chew the tablet.
• The dosage and duration will be determined by your doctor based on your age, body weight, and medical condition.

✔️ Interaction:

The interaction with alcohol is unknown, so it's advised to consult your doctor before consuming alcohol while taking Sulfasalazine.

Several medications could potentially interact with Sulfasalazine, including:

• Methotrexate
• Digoxin
• Insulin
• Diclofenac
• Azathioprine
• Folic Acid
• Etodolac
• Glimepiride It’s important to discuss your current medication list with your doctor to assess these interactions and adjust dosages or medications if necessary.

• Hematologic toxicity: Individuals with blood disorders should avoid Sulfasalazine due to the increased risk of serious side effects.
• Liver disease: If you have liver problems, your doctor may monitor liver function closely and adjust the dose.
• Kidney diseases: Similarly, with pre-existing kidney issues, close monitoring is required, and dose adjustments might be necessary.

There is no specific information available regarding food or lab interactions for Sulfasalazine, so it's best to follow the advice of your healthcare provider.

✔️ Contraindications

Hypersensitivity to Sulfasalazine, its metabolites, sulfonamides or salicylates, patients with intestinal or urinary obstruction, and porphyria.

✔️ Precautions & Warnings

• Pregnancy: Sulfasalazine is generally considered safe during pregnancy, but you should discuss its use with your doctor, particularly if planning to conceive. Your doctor may monitor you more closely, and you may be advised to take additional folic acid or iron supplements to prevent deficiencies, as Sulfasalazine can lower folic acid levels.
• Breastfeeding: Sulfazin 500 should be avoided in breastfeeding mothers because it passes into breast milk and can cause jaundice and brain problems in infants younger than 2 years.
• Allergic Reactions: If you have an allergy to sulfa drugs (such as sulfonamide antibiotics), you may be at risk for serious skin allergies, including urticaria or even severe reactions like Stevens-Johnson syndrome. Always inform your doctor of any drug allergies.
• Effects in Men: Sulfasalazine can lower sperm count in men, but this effect is reversible after discontinuing the medication. If you are planning for fatherhood, you should talk to your doctor.
• Other Health Conditions: If you experience asthma, wheezing, fever, difficulty breathing, severe skin rash, unusual bleeding, sore throat, unexplained bruising, or other symptoms of infection, contact your doctor immediately. These could be signs of a serious reaction to the medication.
• Urine and Skin Changes: It is normal for Sulfasalazine to cause your urine, contact lenses, tears, and skin to take on a yellow or orange hue. This is harmless and temporary. It can also increase sensitivity to sunlight, so you should take precautions to avoid sunburns.

✔️ Storage Conditions:

• Keep Sulfazin out of reach of children
• Store below 25°C